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Elevating Exosome Detection with CD9 Aptamer Biosensor

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  • 2023-10-24
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The Research Team of Professor Lee Taek (Department of Chemical Engineering) Develops a New Biomarker for Exosome Detection and Develops a Biosensor Applying it

- Developed the World’s first Aptamer for Detecting Exosome Surface Protein CD9 -

- Demonstrated the Potential use of biomarkers for Cancer Diagnosis through Exosome detection -

- Published in the prestigious international journal ACS Sensors (IF: 9.618, JCR: 4.1%) - 

 

A research team (Ahn Jung-Yoon, master's student, and Park Hyun-Jun, doctoral student) led by Prof. Lee Taek (Department of Chemical Engineering) has developed a DNA aptamer which can detect Cluster of Differentiation (CD) 9 protein, an exosome surface protein, for the first time and applied it to develop a biosensing platform, which can be used to diagnose cancer.

This research was supported by the Korea Environmental Industry & Technology Institute (2020003030001) through the Aquatic Ecosystem Health Management Program of the Ministry of Environment (MOE), The Industrial Core Technology Development Project (20009121) of the Ministry of Trade, Industry, and Energy, and the National Research Foundation of Korea (2021R1C1C1005583). The research results were published in ACS Sensors, the renowned international academic journal (IF: 9.618, JCR: 4.1%) with the title 'Extended-Gate Field-Effect Transistor Consisted of a CD9 Aptamer and MXene for Exosome Detection in Human Serum' (Reference: https://doi.org/10.1021/acssensors.3c00879)." 

 

광운대 이택 교수(화학공학과) 연구팀, 엑소좀 검출을 위한 신개념 바이오마커 개발 및 이를 적용한 바이오센서 개발