Elevating Exosome Detection with CD9 Aptamer Biosensor
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- 2023-10-24
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The Research Team of Professor Lee Taek (Department of Chemical Engineering) Develops a New Biomarker for Exosome Detection and Develops a Biosensor Applying it
- Developed the World’s first Aptamer
for Detecting Exosome Surface Protein CD9 -
- Demonstrated the Potential use of biomarkers
for Cancer Diagnosis through Exosome detection -
- Published in the prestigious
international journal ACS Sensors (IF: 9.618, JCR: 4.1%) -
A
research team (Ahn Jung-Yoon, master's student, and Park Hyun-Jun, doctoral
student) led by Prof. Lee Taek (Department of Chemical Engineering) has
developed a DNA aptamer which can detect Cluster of Differentiation (CD) 9 protein,
an exosome surface protein, for the first time and applied it to develop a
biosensing platform, which can be used to diagnose cancer.
This
research was supported by the Korea Environmental Industry & Technology
Institute (2020003030001) through the Aquatic Ecosystem Health Management
Program of the Ministry of Environment (MOE), The Industrial Core Technology
Development Project (20009121) of the Ministry of Trade, Industry, and Energy,
and the National Research Foundation of Korea (2021R1C1C1005583). The research
results were published in ACS Sensors, the renowned international academic
journal (IF: 9.618, JCR: 4.1%) with the title 'Extended-Gate Field-Effect
Transistor Consisted of a CD9 Aptamer and MXene for Exosome Detection in Human
Serum' (Reference: https://doi.org/10.1021/acssensors.3c00879)."